TGF alpha Antibody [1E8-G6]

Item no.	PRS-33-212-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Food Safety Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Immunofluorescence Contaminants Primary Antibodies Metals By Organ Skin Cancer Renal Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, IF, IHC
Clone	1E8-G6
Specific against	Human (Homo sapiens), Rabbit (Oryctolagus cuniculus), Carp
Host	Mouse
Isotype	IgM Kappa
Conjugate/Tag	Unconjugated
NCBI	TGFA
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TFGAProtransforming growth factor alpha, EGF-like TGF, TGF-alpha
Available
Manufacturer - Applications	Flow Cytometry: 0.5-1 ug/million cells IF: 1-2 ug/ml IHC (Formalin-paraffin): 1-2 ug/ml for 30 min at RT (1) The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance. 1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Manufacturer - Isotype	IgM, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Growth Factor, Antibody Pairs, Functional Assays
Background	TGF alpha is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. Staining with the antibody is completely blocked by the peptide used for raising this antibody.
Purification	PEG precipitation
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Immunogen	A 10-amino acid synthetic peptide (aa 34-43) from human TGF alpha was used as the immunogen for this antibody.
Clonality	Monoclonal
NCBI Official Name	transforming growth factor, alpha
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/4/2025

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