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CD3 Antibody [B-B12]

CD3 Antibody [B-B12]

Item no.	PRS-33-274-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Flow Cytometry Western Blot Immunofluorescence Autophagy Primary Antibodies By Organ Breast Cancer Testicular & Prostate Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF
Clone	B-B12
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
NCBI	CD3E
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Immunology, Signal Transduction
Background	CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.
By Type	Cancer, Immunology, Signal Transduction
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Flow Cytometry: 0.5-1ug/10e6 cells Immunofluorescence: 1-2 ug/ml Optimal dilution of the CD3 antibody for a specific application should be determined by researcher.
Immunogen	Human T cell leukemia cells were used as immunogen for the CD3 antibody.
Clonality	Monoclonal
NCBI Official Name	CD3e molecule, epsilon (CD3-TCR complex)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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