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Cdc2 Antibody [CDK1/873]

Cdc2 Antibody [CDK1/873]

Item no.	PRS-33-513-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Neuroscience Neuroinflammation Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Cell Biology Flow Cytometry Immunohistochemistry Immunofluorescence Cell Stainings ECM Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, IF, IHC-P
Clone	CDK1/873
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian), Marten, Cattle (Bovine)
Host	Mouse
Isotype	IgG2a Kappa
Conjugate/Tag	Unconjugated
NCBI	CDK1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclin-dependent kinase 1,CDK1,Cell division control protein 2 homolog,Cell division protein kinase 1,p34 protein kinase,CDK1,CDC2,CDC28A,CDKN1,P34CDC2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Cell Cycle, Neuroscience
Background	Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. Cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated Cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
By Type	Cancer, Cell Cycle, Neuroscience
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Flow Cytometry: 0.5-1 ug/million cells in 0.1ml Immunofluorescence: 1-2 ug/ml Immunohistochemistry (FFPE): 2-4 ug/ml for 30 min at RT (1) Optimal dilution of the Cdc2 antibody should be determined by the researcher. 1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Manufacturer - Specificity	Does not react with Mouse, Rat, Xenopus, Drosophila, S. pombe, S. cerevisiae
Immunogen	Recombinant human protein was used as the immunogen for the Cdc2 antibody.
Clonality	Monoclonal
NCBI Official Name	cyclin-dependent kinase 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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