BAFF Antibody [C257/1638]

Primary Antibodies

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

None

0.2 mg/mL

Flow Cytometry: 0.5-1 ug/million cells
IF: 1-2 ug/ml
Titering of the BAFF antibody may be required for optimal performance.

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher