MMP2 Antibody [MMP2/1501]

Primary Antibodies

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.

None

0.2 mg/mL

WB: 0.5-1 ug/ml
The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher