SPTBN2 Antibody [SPTBN2/1584]

Flow Cytometry: 0.5-1ug/10^6 cells in 0.1ml

IF: 0.5-1 ug/ml

IHC (FFPE): 0.5-1 ug/ml for 30 min at RT

WB: 0.5-1 ug/ml



The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Spectrin beta III antibody to be titered up or down for optimal performance.

Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alphaII (fodrin alpha) and spectrin betaI (fodrin beta) are present in other somatic cells. SPTBN2/Spectrin betaIII is highly homologous to both spectrin betaI and spectrin betaII. SPTBN2 is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.

0.2 mg/mL

Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

spectrin beta, non-erythrocytic 2

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.