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Mucin-6 Antibody [MUCN6-1]

Mucin-6 Antibody [MUCN6-1]

Item no.	PRS-33-968-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Immunofluorescence Primary Antibodies Intermediate filaments
Type	Antibody Monoclonal
Format	Liquid
Applications	IF, IHC-P
Clone	MUCN6-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
NCBI	MUC6
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Signal Transduction
Background	Mucin 6 may provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Highest expression seen in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. [UniProt]
By Type	Cancer, Signal Transduction
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Immunofluorescence: 1-2 ug/ml Immunohistochemistry (FFPE): 2-4 ug/ml for 30 min at RT (1) Prediluted format : incubate for 30 min at RT (2) Titering of the Mucin-6 antibody may be required for optimal performance. 1. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining. 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Manufacturer - Specificity	Does not react with rat
Immunogen	Recombinant human protein was used as the immunogen for the Mucin-6 antibody.
Clonality	Monoclonal
NCBI Official Name	mucin 6, oligomeric mucus/gel-forming
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/6/2025

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