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Recombinant NKX2.2 Antibody [RMNK2-1]

Recombinant NKX2.2 Antibody [RMNK2-1]

Item no.	PRS-34-046-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Development Antibodies Obesity Immunohistochemistry Immunofluorescence Enzymes Other Fatty Acid Enzymes Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	IF, IHC
Clone	RMNK2-1
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	NKX2-2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NKX2-2 Antibody: NKX2B,NKX2.2,NKX2B,Homeobox protein NK-2 homolog B
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	IgG, k
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Stem Cell
Background	NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]
By Type	Stem Cell
Badges	Recombinant
Modifications	None
Purification	Protein A affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	IF: 0.5-1 ug/ml IHC (FFPE): 0.5-1 ug/ml for 30 minutes at RT (1) Titering of the NKX2.2 antibody may be required for optimal performance. 1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Immunogen	A human partial recombinant protein was used as the immunogen for this rabbit monoclonal NKX2.2 antibody.
Clonality	Recombinant Monoclonal
NCBI Official Name	NK2 homeobox 2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 2/5/2026

Express Delivery: Save 29 days

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