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Recombinant CD20 Antibody [RMC20-1]

Recombinant CD20 Antibody [RMC20-1]

Item no.	PRS-34-059-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Immunohistochemistry Primary Antibodies By Organ Bladder Cancer Gastric Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	IHC
Clone	RMC20-1
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	MS4A1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	B-lymphocyte antigen CD20,B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1,CD20,MS4A1,CD20
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	IgG, kappa
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Immunology, Signal Transduction
Background	CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It has been shown that CD20 plays a role in the microenvironmental interactions of B cells. [Wiki]
By Type	Cancer, Immunology, Signal Transduction
Badges	Recombinant
Modifications	None
Purification	Protein A affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Immunohistochemistry (FFPE): 0.5-1 ug/ml for 30 minutes at RT Prediluted IHC only format: incubate for 30 min at RT (1) Titering of the recombinant CD20 antibody may be required for optimal performance. 1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Immunogen	Full length human CD20 protein was used as the immunogen for this reccombinant CD20 antibody.
Clonality	Recombinant Monoclonal
NCBI Official Name	membrane-spanning 4-domains, subfamily A, member 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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