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Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

Item no.	PRS-34-063-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Myelofibrosis Flow Cytometry Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, IF, IHC-P
Clone	PDCD1/1410R
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PDCD1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	PD-1 Antibody: PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,PD1,Programmed cell death protein 1,Protein PD-1,PDCD1,PDCD-1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	IgG, k
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Immunology, Cancer, Cell Cycle
Background	PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
By Type	Immunology, Cancer, Cell Cycle
Badges	Recombinant
Modifications	None
Purification	Protein A affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Immunohistochemistry (FFPE): 1-2 ug/ml for 30 min at RT Prediluted IHC only format: incubate for 30 min at RT (1) Immunofluorescence: 1-2 ug/ml Flow Cytometry: 0.5-1ug/10e6 cells in 0.1ml Titering of the recombinant PD1 antibody may be required for optimal performance. 1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Immunogen	A partial length human protein was used as the immunogen for the recombinant PD1 antibody.
Clonality	Recombinant Monoclonal
NCBI Official Name	programmed cell death 1
NCBI Organism	mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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