Recombinant NKX2.2 Antibody [NX2/1422R]

IgG, k

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Recombinant

Protein A affinity chromatography

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

A human partial recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.

NK2 homeobox 2

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.