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Sirtuin 2 Antibody [S2R233-1]

Sirtuin 2 Antibody [S2R233-1]

Item no.	PRS-36-077-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Food Safety Allergenes Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, ELISA
Clone	S2R233-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Conjugate/Tag	Unconjugated
NCBI	SIRT2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SIRT2; NAD-dependent Deacetylase Sirtuin-2; SIR2-like protein 2; SIR2L2
Available
Manufacturer - Applications	ELISA: (direct and indirect: 1:2, 000-1:5, 000). Western Blot: (1:2, 000-1:5, 000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Shipping Temperature	blue ice or room temperature
Storage Conditions	Stable for at least 1 year after receipt when stored at -20°C.
Manufacturer - Research Area	Cancer, Innate Immunity, Obesity
Background	Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer’s disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington’s and Parkinson’s disease.
Protein Gi #	NP_036369
Concentration	1 mg/ml
Buffer	Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Immunogen	Recombinant human sirtuin 2.
Clonality	Monoclonal
NCBI Official Name	sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/4/2025

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