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TRAIL-R2 Antibody [HS201]

TRAIL-R2 Antibody [HS201]

Item no.	PRS-36-128-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Immunoprecipitation Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	FC, IP, IHC, ICC, FA
Clone	HS201
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
NCBI	TNFRSF10B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TRAIL Receptor 2,DR5,KILLER,TNFRSF10B,CD262
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies, Functional Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C.
Manufacturer - Research Area	Cancer, Immunology, Functional Assays
Background	TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
By Type	Cancer, Immunology
Modifications	None
Protein Gi #	AF012535
Purification	>95% (SDS-PAGE)
Concentration	1 mg/ml
Buffer	Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Application Note	Functional Application: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution). Immunohistochemistry: (paraffin sections, 15ug/ml).
Manufacturer - Specificity	Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
Immunogen	Recombinant human TRAIL-R2 (DR5).
Clonality	Monoclonal
NCBI Official Name	tumor necrosis factor receptor superfamily, member 10b
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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