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TRAIL-R2 Antibody [HS201] (ATTO 647N)

TRAIL-R2 Antibody [HS201] (ATTO 647N)

Item no.	PRS-36-133-100tests
Manufacturer	ProSci
Amount	100 tests
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis Flow Cytometry Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	FC, ICC
Clone	HS201
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
NCBI	TNFRSF10B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TRAIL Receptor 2,DR5,KILLER,TNFRSF10B,CD262
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Conjugate / Tag	ATTO 647N
Shipping Temperature	Blue Ice
Storage Conditions	Keep conjugated formats at +4˚ C. Stable for at least 1 year after receipt when stored at +4˚ C.
Manufacturer - Research Area	Cancer, Immunology
Background	TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
By Type	Cancer, Immunology
Modifications	None
Protein Gi #	AF012535
Purification	>95% (SDS-PAGE)
Concentration	1 mg/ml
Buffer	Liquid. In PBS containing 0.02% sodium azide.
Application Note	Definition for 1 test: 1ul of labeled antibody in 200ul of Flow Cytometry buffer (see online protocol).
Manufacturer - Specificity	Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
Immunogen	Recombinant human TRAIL-R2 (DR5).
Clonality	Monoclonal
NCBI Official Name	tumor necrosis factor receptor superfamily, member 10b
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests

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Delivery expected until 1/1/2026

Express Delivery: Save 27 days

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