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PIDD Antibody

PIDD Antibody

Item no.	PRS-36-329-50ug
Manufacturer	ProSci
Amount	50 ug
Category	Oncology Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
NCBI	PIDD1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	p53-induced Protein with a Death Domain,Leucine-rich Repeat and Death Domain-containing Protein,Lrdd
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C.
Manufacturer - Research Area	Apoptosis, Cancer, Innate Immunity
Background	PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
By Type	Apoptosis, Cancer, Innate Immunity
Modifications	None
Protein Gi #	Q9HB75
Concentration	1 mg/ml
Buffer	Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Application Note	Immunohistochemistry: (paraffin sections). Immunoprecipitation: (1:100). Western Blot: (1:500).
Manufacturer - Specificity	Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot.
Immunogen	Recombinant human PIDD (Death Domain: aa 776-910).
Clonality	Polyclonal
NCBI Official Name	p53-induced death domain protein 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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