Comparison

Tropomyosin-1a (Ser 283) Antibody

Item no. PRS-39-877-0.05mg
Manufacturer ProSci
Amount 0.05 mg
Category
Type Antibody Primary
Format Lyophilized
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus domesticus), Primate
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat. Yuan, C., Sheng, Q., Tang, H.,Tixue, L., Zeng, R., and Solaro, R.J.. Am J Physiol Heart Circ Physiol.2008; 295: H647-H656.
p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity.Vahebi S, Ota A, Li M, Warren CM, de Tombe PP, Wang Y, Solaro RJ. Circ Res. 2007 Feb 16;100(3):408-15.
NCBI TPM1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tropomyosin-1 (alpha),phospho serine 283,CMH3,TMSA,CMD1Y,LVNC9,C15orf13,HTM-alpha
Shipping Condition Room temperature
Available
Specificity Human, Mouse, Rat, Chicken, Non-Human Primate
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Room Temp
Manufacturer - Research Area
Phospho-Specific
Background
Tropomyosin (Tpm-1)consists of a family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction..
By Type
Phospho-Specific
Modifications
Phospho-Specific
Protein Gi #
136092
Purification
Affinity Purified
Concentration
batch dependent
Application Note
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Immunogen
A synthetic phosphopeptide corresponding to the region surrounding S283.
Clonality
Polyclonal
NCBI Official Name
tropomyosin 1 (alpha)
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.05 mg
Available: In stock
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