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Lamin B1 Antibody

Lamin B1 Antibody

Item no.	PRS-43-160-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Signaling Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Caprine
Conjugate/Tag	Unconjugated
Citations	Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N.Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms.
NCBI	Lamin B1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	LMNB1,lamin B1,ADLD,LMN,LMN2,LMNB,MGC111419,OTTHUMP00000159218,lamin-B1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and store at -20˚ C. Minimize freezing and thawing.
Molecular Weight	Approx 70kDa
Manufacturer - Research Area	Neuroscience, Obesity, Signal Transduction
By Type	Neuroscience, Obesity, Signal Transduction
Modifications	None
Protein Gi #	125953
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration	500 ug/mL
Buffer	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Application Note	Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 70kDa band observed in nuclear lysates of cell lines HeLa and Jurkat and approx. 70-75kDa in Mouse Liver lysates (calculated MW of 66.4kDa according to Human NP_005564.1 and 66.8kDa according to Mouse NP_034851.2) Recommended concentration: 1-3ug/ml.
Homology	Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
Manufacturer - Specificity	This antibody is expected to recognize both reported isoforms (NP_005564.1; NP_001185486.1).
Immunogen	The immunogen for this antibody is: C-DVKVILKNSQGE
Clonality	Polyclonal
NCBI Official Name	lamin B1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 2/5/2026

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