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GLuR5 Antibody

GLuR5 Antibody

Item no.	PRS-45-679-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot ELISA Primary Antibodies By Organ Brain Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Caprine
Conjugate/Tag	Unconjugated
Citations	Martin S, Nishimune A, Mellor JR, Henley JM. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature. 2007 May 17;447(7142):321-5. Epub 2007 May 7.
NCBI	GRIK1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GLUR5,GRIK1,glutamate receptor,ionotropic,kainate 1,EAA3 ,EEA3 ,GLR5 ,excitatory amino acid receptor 3
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and store at -20˚ C. Minimize freezing and thawing.
Manufacturer - Research Area	Cancer
By Type	Cancer
Modifications	None
Protein Gi #	4504117
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Positive Control 1	PRS-1362-0.1mg
Concentration	500 ug/mL
Buffer	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Application Note	Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 150kDa band observed in Human Brain (Cerebellum and Cerebral Cortex) lysates (calculated MW of 104kDa according to NP_000821.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Christensen et al , J Neurosci. 2004 Oct 13; 24(41):8986-93.; PMID: 15483117). Recommended concentration: 1-3ug/ml. Primary incubation was 1 hour. An additional very strong band of unknown identity was also consistently observed at 60kDa. This band was successfully blocked by incubation with the immunising peptide.Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 3.75ug/ml.
Homology	Expected Species Reactivity based on sequence homology: Mouse, Rat
Manufacturer - Specificity	This antibody is expected to recognise both reported isoforms according to NP_000821.1 and NP_783300.1.
Immunogen	The immunogen for this antibody is: QCKQTHPTNSTS
Clonality	Polyclonal
NCBI Official Name	glutamate receptor, ionotropic, kainate 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 2/5/2026

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