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Comparison

Desmin Antibody

Item no. PRS-46-777-0.1mg
Manufacturer ProSci
Amount 0.1 mg
Category
Type Antibody Primary
Format Liquid
Applications WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Pig (Porcine, Sus scrofa domesticus)
Host Caprine
Conjugate/Tag Unconjugated
Citations Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL. Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis. J Biol Chem. 2003 Feb 28;278(9):6848-53.
NCBI DES
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DES,desmin,CMD1I,CSM1,CSM2,FLJ12025,FLJ39719,FLJ41013,FLJ41793,intermediate filament protein
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Aliquot and store at -20˚ C. Minimize freezing and thawing.
Manufacturer - Research Area
Signal Transduction , Stem Cell
By Type
Signal Transduction, Stem Cell
Modifications
None
Protein Gi #
55749932
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Positive Control 1
PRS-1461-0.1mg
Concentration
500 ug/mL
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing.
Application Note
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 55-60kDa band observed in Human, Mouse, Rat and Pig Skeletal Muscle lysates (calculated MW of 53.5kDa according to Human NP_001918.3, Mouse NP_034173.1, Rat NP_071976.1 and 53.6kDa according to Pig NP_001001535.1). Recommended concentration: 0.3-1ug/ml.Immunohistochemistry:Paraffin embedded Human Heart and Skeletal Muscle. Recommended concentration: 5ug/ml. In paraffin embedded Human Heart, expression of Desmin is detected in myocardial muscle and not in adjacent vascular smooth muscle. Recommended concentration:3.75ug/ml. Data obtained from previous batch.
Homology
Expected Species Reactivity based on sequence homology: Dog, Cow
Immunogen
The immunogen for this antibody is: C-RDGEVVSEATQQQHE
Clonality
Polyclonal
NCBI Official Name
desmin
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg
Available: In stock
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