Comparison

Neurofilament NF-H Antibody [NAP4]

Item no. PRS-50-253-0.1mL
Manufacturer ProSci
Amount 0.1 mL
Category
Type Antibody Primary
Format Liquid
Applications WB, IHC
Clone NAP4
Specific against Chicken (Gallus gallus domesticus)
Host Mouse
Conjugate/Tag Unconjugated
Citations Harris, J., Ayyub, C. and Shaw G. (1991) A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. J Neurosci Res 30:47-62.
Mendonca DM, Chimelli L, Martinez AM. (2005) Quantitative evidence for neurofilamentheavy subunit aggregation in motor neurons of spinal cords of patients with amyotrophic lateral sclerosis. Braz J Med Biol Res. 38(6):925-933.
Hu YY, He SS, Wang XC, Duan QH, Khatoon S, Igbal K, Grundke-Igbal I, Wang JZ (2002) Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients. Neurosci Lett 320(3):156-60.
NCBI NEFH
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Specificity Chicken, Mammal
Shipping Temperature
blue ice or room temperature
Storage Conditions
Neurofilament NF-H antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
Molecular Weight
200
Manufacturer - Research Area
Neuroscience
Background
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
Protein Gi #
226726294
Purification
Total IgG fraction
Immunogen
Purified bovine NF-H.
Clonality
Monoclonal
NCBI Official Name
neurofilament, heavy polypeptide
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mL
Available: In stock
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