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GABBR2 Antibody

GABBR2 Antibody

Item no.	PRS-55-090-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Heart & Blood Cancer Renal Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Oblak, A.L., et al. J. Neurochem. 114(5):1414-1423(2010) Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
NCBI	GABBR2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20, GABBR2, GPR51, GPRC3B
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	106 kDa
Manufacturer - Research Area	Neuroscience, Growth Factor
Background	The multi-pass membrane protein encoded by this genebelongs to the G-protein coupled receptor 3 family and GABA-Breceptor subfamily. The GABA-B receptors inhibit neuronal activitythrough G protein-coupled second-messenger systems, which regulatethe release of neurotransmitters, and the activity of ion channelsand adenylyl cyclase. This receptor subunit forms an activeheterodimeric complex with GABA-B receptor subunit 1, neither ofwhich is effective on its own. Allelic variants of this gene havebeen associated with nicotine dependence.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Rat
Immunogen	This GABBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-890 amino acids from the C-terminal region of human GABBR2.
Clonality	Polyclonal
NCBI Official Name	Gamma-aminobutyric acid type B receptor subunit 2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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