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BCKDHB Antibody

BCKDHB Antibody

Item no.	PRS-55-327-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cell Status Apoptosis Cytoskeleton Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Gorzelany, K., et al. Turk. J. Pediatr. 51(2):97-102(2009) Quental, S., et al. Mol. Genet. Metab. 94(2):148-156(2008) Kang, H., et al. Fertil. Steril. 89(3):728-731(2008)
NCBI	BCKDHB
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	2-oxoisovalerate dehydrogenase subunit beta,mitochondrial,Branched-chain alpha-keto acid dehydrogenase E1 component beta chain,BCKDE1B,BCKDH E1-beta,BCKDHB
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	43 kDa
Manufacturer - Research Area	Obesity, Signal Transduction
Background	Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism of branched-chain amino acids. The complex consists of multiple copies of 3 components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). This gene encodes the E1 beta subunit, and mutations therein have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation, and feeding problems.
By Type	Obesity, Signal Transduction
Modifications	None
Protein Gi #	129034
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Immunogen	This BCKDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human BCKDHB.
Clonality	Polyclonal
NCBI Official Name	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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