FBXW8 Antibody

Primary Antibodies

Blue Ice

67 kDa

This gene encodes a member of the F-box protein family,
members of which are characterized by an approximately 40 amino
acid motif, the F-box. The F-box proteins constitute one of the
four subunits of ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into three classes:
Fbws containing WD-40 domains, Fbls containing leucine-rich
repeats, and Fbxs containing either different protein-protein
interaction modules or no recognizable motifs. The protein encoded
by this gene contains a WD-40 domain, in addition to an F-box
motif, so it belongs to the Fbw class. Alternatively spliced
transcript variants encoding distinct isoforms have been identified
for this gene.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This FBXW8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of human FBXW8.

F-box/WD repeat-containing protein 8

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.