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KARS Antibody

KARS Antibody

Item no.	PRS-55-623-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	McLaughlin, H.M., et al. Am. J. Hum. Genet. 87(4):560-566(2010) Kepp, O., et al. Cell Cycle 9(15):3072-3077(2010) Segat, L., et al. Vaccine 28(10):2201-2206(2010) Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
NCBI	KARS
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Lysine--tRNA ligase,Lysyl-tRNA synthetase,LysRS,KARS,KIAA0070
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	68 kDa
Manufacturer - Research Area	Cancer, Neuroscience, Signal Transduction
Background	Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
By Type	Cancer, Neuroscience, Signal Transduction
Modifications	None
Protein Gi #	20178333
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Immunogen	This KARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human KARS.
Clonality	Polyclonal
NCBI Official Name	Lysine--tRNA ligase
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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