ETFA Antibody

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

blue ice or room temperature

35 kDa

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.

Electron transfer flavoprotein subunit alpha, mitochondrial

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.