MNDA Antibody

Primary Antibodies

Blue Ice

46 kDa

The myeloid cell nuclear differentiation antigen (MNDA) is
detected only in nuclei of cells of the granulocyte-monocyte
lineage. A 200-amino acid region of human MNDA is strikingly
similar to a region in the proteins encoded by a family of
interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and
Ifi-203, that are not regulated in a cell- or tissue-specific
fashion. The 1.8-kb MNDA mRNA, which contains an
interferon-stimulated response element in the 5-prime untranslated
region, was significantly upregulated in human monocytes exposed to
interferon alpha. MNDA is located within 2, 200 kb of FCER1A, APCS,
CRP, and SPTA1. In its pattern of expression and/or regulation,
MNDA resembles IFI16, suggesting that these genes participate in
blood cell-specific responses to interferons.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This MNDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human MNDA.

Myeloid cell nuclear differentiation antigen

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.