Comparison

GUCY2D Antibody

Item no. PRS-55-919-400ul
Manufacturer ProSci
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, FC, IHC-P
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Conjugate/Tag Unconjugated
Citations Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Pasadhika, S., et al. Invest. Ophthalmol. Vis. Sci. 51(5):2608-2614(2010)
NCBI GUCY2D
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Retinal guanylyl cyclase 1,RETGC-1,Guanylate cyclase 2D,retinal,Rod outer segment membrane guanylate cyclase,ROS-GC,GUCY2D,CORD6,GUC1A4,GUC2D,RETGC,RETGC1
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
120 kDa
Manufacturer - Research Area
Neuroscience, Signal Transduction
Background
This gene encodes a retina-specific guanylate cyclase,
which is a member of the membrane guanylyl cyclase family. Like
other membrane guanylyl cyclases, this enzyme has a hydrophobic
amino-terminal signal sequence followed by a large extracellular
domain, a single membrane spanning domain, a kinase homology
domain, and a guanylyl cyclase catalytic domain. In contrast to
other membrane guanylyl cyclases, this enzyme is not activated by
natriuretic peptides. Mutations in this gene result in Leber
congenital amaurosis and cone-rod dystrophy-6 diseases. [provided
by RefSeq].
By Type
Neuroscience, Signal Transduction
Modifications
None
Protein Gi #
1345920
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Immunogen
This GUCY2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D.
Clonality
Polyclonal
NCBI Official Name
Retinal guanylyl cyclase 1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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