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PDE1B Antibody

PDE1B Antibody

Item no.	PRS-56-074-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Enzymes Prostaglandin Synthases Oxidative Stress Primary Antibodies By Organ Testicular & Prostate Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Vandeput, F., et al. J. Biol. Chem. 282(45):32749-32757(2007) Bender, A.T., et al. Proc. Natl. Acad. Sci. U.S.A. 103(2):460-465(2006)
NCBI	PDE1B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE, PDE1B, PDE1B1, PDES1B
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	61 kDa
Manufacturer - Research Area	Signal Transduction
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyzehydrolysis of the cyclic nucleotides cAMP and cGMP to thecorresponding nucleoside 5-prime-monophosphates. Mammalian PDEshave been classified into several families based on theirbiochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that arestimulated by a calcium-calmodulin complex (Repaske et al., 1992[PubMed 1326532]).
Protein Gi #	3183514
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This PDE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human PDE1B.
Clonality	Polyclonal
NCBI Official Name	Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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