TGFBR2 Antibody

For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000

blue ice or room temperature

65 kDa

This gene encodes a member of the Ser/Thr protein kinasefamily and the TGFB receptor subfamily. The encoded protein is atransmembrane protein that has a protein kinase domain, forms aheterodimeric complex with another receptor protein, and bindsTGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of asubset of genes related to cell proliferation. Mutations in thisgene have been associated with Marfan Syndrome, Loeys-Deitz AorticAneurysm Syndrome, and the development of various types of tumors.Alternatively spliced transcript variants encoding differentisoforms have been characterized.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Polyclonal

Homo sapiens