TGFBR2 Antibody

Primary Antibodies

Blue Ice

65 kDa

This gene encodes a member of the Ser/Thr protein kinase
family and the TGFB receptor subfamily. The encoded protein is a
transmembrane protein that has a protein kinase domain, forms a
heterodimeric complex with another receptor protein, and binds
TGF-beta. This receptor/ligand complex phosphorylates proteins,
which then enter the nucleus and regulate the transcription of a
subset of genes related to cell proliferation. Mutations in this
gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic
Aneurysm Syndrome, and the development of various types of tumors.
Alternatively spliced transcript variants encoding different
isoforms have been characterized.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This TGFBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human TGFBR2.

TGF-beta receptor type-2

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.