GDF5 Antibody

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

blue ice or room temperature

55 kDa

The protein encoded by this gene is a member of the bonemorphogenetic protein (BMP) family and the TGF-beta superfamily.This group of proteins is characterized by a polybasic proteolyticprocessing site which is cleaved to produce a mature proteincontaining seven conserved cysteine residues. The members of thisfamily are regulators of cell growth and differentiation in bothembryonic and adult tissues. Mutations in this gene are associatedwith acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associationsconfirm that the gene product plays a role in skeletal development.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human GDF5.

Growth/differentiation factor 5

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.