VEGFA Antibody

Primary Antibodies

Blue Ice

27 kDa

This gene is a member of the PDGF/VEGF growth factor
family and encodes a protein that is often found as a disulfide
linked homodimer. This protein is a glycosylated mitogen that
specifically acts on endothelial cells and has various effects,
including mediating increased vascular permeability, inducing
angiogenesis, vasculogenesis and endothelial cell growth, promoting
cell migration, and inhibiting apoptosis. Elevated levels of this
protein is linked to POEMS syndrome, also known as Crow-Fukase
syndrome. Mutations in this gene have been associated with
proliferative and nonproliferative diabetic retinopathy.
Alternatively spliced transcript variants, encoding either freely
secreted or cell-associated isoforms, have been characterized.
There is also evidence for the use of non-AUG (CUG) translation
initiation sites upstream of, and in-frame with the first AUG,
leading to additional isoforms.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human VEGFA.

Vascular endothelial growth factor A

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.