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CHRNA10 Antibody

CHRNA10 Antibody

Item no.	PRS-56-266-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Melanoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Saccone, N.L., et al. Genes Brain Behav. 9(7):741-750(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Rigbi, A., et al. Pharmacogenomics J. (2010) In press : Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
NCBI	CHRNA10
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neuronal acetylcholine receptor subunit alpha-10,Nicotinic acetylcholine receptor subunit alpha-10,NACHR alpha-10,CHRNA10,NACHRA10
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	50 kDa
Manufacturer - Research Area	Neuroscience, Signal Transduction
Background	CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
By Type	Neuroscience, Signal Transduction
Modifications	None
Protein Gi #	14916526
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For IHC-P starting dilution is: 1:10~50 For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Rat
Immunogen	This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10.
Clonality	Polyclonal
NCBI Official Name	Neuronal acetylcholine receptor subunit alpha-10
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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