SNX13 Antibody

Primary Antibodies

Blue Ice

112 kDa

This gene encodes a PHOX domain- and RGS domain-containing
protein that belongs to the sorting nexin (SNX) family and the
regulator of G protein signaling (RGS) family. The PHOX domain is a
phosphoinositide binding domain, and the SNX family members are
involved in intracellular trafficking. The RGS family members are
regulatory molecules that act as GTPase activating proteins for G
alpha subunits of heterotrimeric G proteins. The RGS domain of this
protein interacts with G alpha(s), accelerates its GTP hydrolysis,
and attenuates G alpha(s)-mediated signaling. Overexpression of
this protein delayes lysosomal degradation of the epidermal growth
factor receptor. Because of its bifunctional role, this protein may
link heterotrimeric G protein signaling and vesicular trafficking.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.