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Ubiquitin Antibody

Ubiquitin Antibody

Item no.	PRS-56-332-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Chan, Y.L., et al., Biochem. Biophys. Res. Commun. 215(2):682-690 (1995). Cook, W.J., et al., J. Mol. Biol. 236(2):601-609 (1994). Hubbard, M.J., et al., Biochim. Biophys. Acta 1200(2):191-196 (1994). Wajih, N., et al., Protein Seq. Data Anal. 5(1):31-32 (1992).
NCBI	UBC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Polyubiquitin-C,Ubiquitin,UBC
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	77 kDa
Manufacturer - Research Area	Cell Cycle, Neuroscience
Background	This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
By Type	Cell Cycle, Neuroscience
Modifications	None
Protein Gi #	391358178
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For IF starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Yeast, Xenopus, Bovine, C. Elegans, Drosophila
Immunogen	This Ubiquitin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-66 amino acids of human Ubiquitin.
Clonality	Polyclonal
NCBI Official Name	Polyubiquitin-C
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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