RASAL1 Antibody

Primary Antibodies

Blue Ice

90 kDa

The protein encoded by this gene is member of the GAP1
family of GTPase-activating proteins. These proteins stimulate the
GTPase activity of normal RAS p21 but not its oncogenic
counterpart. Acting as a suppressor of RAS function, the protein
enhances the weak intrinsic GTPase activity of RAS proteins
resulting in the inactive GDP-bound form of RAS, thereby allowing
control of cellular proliferation and differentiation. This
particular family member contains domains which are characteristic
of the GAP1 subfamily of RasGAP proteins but, in contrast to the
other GAP1 family members, this protein is strongly and selectively
expressed in endocrine tissues. Alternatively spliced transcript
variants that encode different isoforms have been described

None

batch dependent

For WB starting dilution is: 1:1000

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.