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PREX1 Antibody

PREX1 Antibody

Item no.	PRS-56-514-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Astrocytoma By Organ Bladder Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Lewis, J.P., et al. Genomics 96(4):211-219(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Nie, B., et al. Cell. Signal. 22(5):770-782(2010) Carretero-Ortega, J., et al. Mol. Pharmacol. 77(3):435-442(2010)
NCBI	PREX1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein,P-Rex1,PtdIns(3,5)-dependent Rac exchanger 1,PREX1,KIAA1415
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	186 kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3, 4, 5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
By Type	Cell Cycle, Signal Transduction
Modifications	None
Protein Gi #	148886999
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For FACS starting dilution is: 1:25 For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:1000
Immunogen	This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1.
Clonality	Polyclonal
NCBI Official Name	Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 1 protein
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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