LOXL3 Antibody

Primary Antibodies

Blue Ice

83 kDa

This gene encodes a member of the lysyl oxidase gene
family. The prototypic member of the family is essential to the
biogenesis of connective tissue, encoding an extracellular
copper-dependent amine oxidase that catalyses the first step in the
formation of crosslinks in collagens and elastin. A highly
conserved amino acid sequence at the C-terminus end appears to be
sufficient for amine oxidase activity, suggesting that each family
member may retain this function. The N-terminus is poorly conserved
and may impart additional roles in developmental regulation,
senescence, tumor suppression, cell growth control, and chemotaxis
to each member of the family. Alternatively spliced transcript
variants of this gene have been reported but their full-length
nature has not been determined.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.