COCH Antibody

Primary Antibodies

Blue Ice

59 kDa

The protein encoded by this gene is highly conserved in
human, mouse, and chicken, showing 94% and 79% amino acid identity
of human to mouse and chicken sequences, respectively.
Hybridization to this gene was detected in spindle-shaped cells
located along nerve fibers between the auditory ganglion and
sensory epithelium. These cells accompany neurites at the habenula
perforata, the opening through which neurites extend to innervate
hair cells. This and the pattern of expression of this gene in
chicken inner ear paralleled the histologic findings of acidophilic
deposits, consistent with mucopolysaccharide ground substance, in
temporal bones from DFNA9 (autosomal dominant nonsyndromic
sensorineural deafness 9) patients. Mutations that cause DFNA9 have
been reported in this gene. Alternative splicing results in
multiple transcript variants encoding the same protein. Additional
splice variants encoding distinct isoforms have been described but
their biological validities have not been demonstrated. [provided
by RefSeq].

None

batch dependent

For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50

This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human COCH.

Cochlin

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.