RAP1A Antibody

For WB starting dilution is: 1:1000

blue ice or room temperature

21 kDa

The product of this gene belongs to the family ofRAS-related proteins. These proteins share approximately 50% aminoacid identity with the classical RAS proteins and have numerousstructural features in common. The most striking difference betweenRAP proteins and RAS proteins resides in their 61st amino acid:glutamine in RAS is replaced by threonine in RAP proteins. Theproduct of this gene counteracts the mitogenic function of RASbecause it can interact with RAS GAPs and RAF in a competitivemanner. Two transcript variants encoding the same protein have beenidentified for this gene.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This RAP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the C-terminal region of human RAP1A.

Ras-related protein Rap-1A

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.