SCD5 Antibody

For WB starting dilution is: 1:1000

blue ice or room temperature

38 kDa

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integralmembrane protein of the endoplasmic reticulum that catalyzes theformation of monounsaturated fatty acids from saturated fattyacids. SCD may be a key regulator of energy metabolism with a rolein obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limitedhomology with the rodent SCDs and appears to be unique to primates(Wang et al., 2005 [PubMed 15907797]).

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SCD5.

Stearoyl-CoA desaturase 5

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.