UNC13B Antibody

Primary Antibodies

Blue Ice

181 kDa

This gene is expressed in the kidney cortical epithelial
cells and is upregulated by hyperglycemia. The encoded protein
shares a high level of similarity to the rat homolog, and contains
3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia
increases the levels of diacylglycerol, which has been shown to
induce apoptosis in cells transfected with this gene and thus
contribute to the renal cell complications of hyperglycemia.
Studies in other species also indicate a role for this protein in
the priming step of synaptic vesicle exocytosis. [provided by
RefSeq].

None

batch dependent

For WB starting dilution is: 1:1000

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.