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BNIP3 Antibody

BNIP3 Antibody

Item no.	PRS-56-927-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Hematology Leukemia Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	References for protein: Kothari, S., et al., Oncogene 22(30):4734-4744 (2003). Lee, S.M., et al., Life Sci. 71(19):2267-2277 (2002). Ray, R., et al., J. Biol. Chem. 275(2):1439-1448 (2000).
NCBI	BNIP3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Available
Manufacturer - Applications	For IF starting dilution is: 1:500 For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	22 kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Obesity, Autophagy
Background	NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Protein Gi #	20532402
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-187 amino acids from human BNIP3.
Clonality	Polyclonal
NCBI Official Name	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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