Comparison

OGDH Antibody

Item no. PRS-57-045-400ul
Manufacturer ProSci
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Conjugate/Tag Unconjugated
Citations van Bever, Y., et al. Am. J. Med. Genet.143(7):763-767(2007)
Shi, Q., et al. J. Biol. Chem. 280(12):10888-10896(2005)
Habelhah, H., et al. J. Biol. Chem. 279(51):53782-53788(2004)
McCartney, R.G., et al. J. Biol. Chem. 273(37):24158-24164(1998)
NCBI OGDH
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase, OGDH
Available
Manufacturer - Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
116 kDa
Manufacturer - Research Area
Obesity, Signal Transduction
Background
This gene encodes one subunit of the 2-oxoglutaratedehydrogenase complex. This complex catalyzes the overallconversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoAand CO(2) during the Krebs cycle. The protein is located in themitochondrial matrix and uses thiamine pyrophosphate as a cofactor.A congenital deficiency in 2-oxoglutarate dehydrogenase activity isbelieved to lead to hypotonia, metabolic acidosis, andhyperlactatemia. Alternative splicing results in multipletranscript variants encoding distinct isoforms.
Protein Gi #
160332299
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This OGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of human OGDH.
Clonality
Polyclonal
NCBI Official Name
2-oxoglutarate dehydrogenase, mitochondrial
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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