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PTPLA Antibody

PTPLA Antibody

Item no.	PRS-57-074-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Hematology Leukemia Myelofibrosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Liang, X., et al. Hum. Mutat. 30(3):463-471(2009) Lamesch, P., et al. Genomics 89(3):307-315(2007)
NCBI	PTPLA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1,3-hydroxyacyl-CoA dehydratase 1,HACD1,Cementum attachment protein,Protein-tyrosine phosphatase-like member A,PTPLA,HACD1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	32 kDa
Manufacturer - Research Area	Obesity, Signal Transduction
Background	The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation.
By Type	Obesity, Signal Transduction
Modifications	None
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Immunogen	This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
Clonality	Polyclonal
NCBI Official Name	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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