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SMC1A Antibody

SMC1A Antibody

Item no.	PRS-57-109-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Limongelli, G., et al. Am. J. Med. Genet.152A (8), 2127-2129 (2010) : Homme, C., et al. Oncol. Rep. 24(1):47-56(2010) Pie, J., et al. Am. J. Med. Genet.152A (4), 924-929 (2010) : Wong, R.W. Cell Cycle 9(1):198-200(2010)
NCBI	SMC1A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Structural maintenance of chromosomes protein 1A,SMC protein 1A,SMC-1-alpha,SMC-1A,Sb18,SMC1A,DXS423E,KIAA0178,SB18,SMC1,SMC1L1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	143 kDa
Manufacturer - Research Area	Cell Cycle
Background	Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq].
By Type	Cell Cycle
Modifications	None
Protein Gi #	29336622
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen	This SMC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the N-terminal region of human SMC1A.
Clonality	Polyclonal
NCBI Official Name	Structural maintenance of chromosomes protein 1A
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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