DOK7 Antibody

Primary Antibodies

Blue Ice

53 kDa

The protein encoded by this gene is essential for
neuromuscular synaptogenesis. The protein functions in aneural
activation of muscle-specific receptor kinase, which is required
for postsynaptic differentiation, and in the subsequent clustering
of the acetylcholine receptor in myotubes. This protein can also
induce autophosphorylation of muscle-specific receptor kinase.
Mutations in this gene are a cause of familial limb-girdle
myasthenia autosomal recessive, which is also known as congenital
myasthenic syndrome type 1B. Alternative splicing results in
multiple transcript variants.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.

Protein Dok-7

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.