KRT6B Antibody

Primary Antibodies

Blue Ice

60 kDa

The protein encoded by this gene is a member of the
keratin gene family. The type II cytokeratins consist of basic or
neutral proteins which are arranged in pairs of heterotypic keratin
chains coexpressed during differentiation of simple and stratified
epithelial tissues. As many as six of this type II cytokeratin
(KRT6) have been identified; the multiplicity of the genes is
attributed to successive gene duplication events. The genes are
expressed with family members KRT16 and/or KRT17 in the filiform
papillae of the tongue, the stratified epithelial lining of oral
mucosa and esophagus, the outer root sheath of hair follicles, and
the glandular epithelia. Mutations in these genes have been
associated with pachyonychia congenita. The type II cytokeratins
are clustered in a region of chromosome 12q12-q13. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This KRT6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the Central region of human KRT6B.

Keratin, type II cytoskeletal 6B

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.