CENPA Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Centromeres are the differentiated chromosomal domains
that specify the mitotic behavior of chromosomes. CENPA encodes a
centromere protein which contains a histone H3 related histone fold
domain that is required for targeting to the centromere. CENPA is
proposed to be a component of a modified nucleosome or
nucleosome-like structure in which it replaces 1 or both copies of
conventional histone H3 in the (H3-H4)2 tetrameric core of the
nucleosome particle. Alternative splicing results in multiple
transcript variants encoding distinct isoforms. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine, Hamster

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.