MDM4 Antibody

Primary Antibodies

Blue Ice

55 kDa

The human MDM4 gene, which plays a role in apoptosis,
encodes a 490-amino acid protein containing a RING finger domain
and a putative nuclear localization signal. The MDM4 putative
nuclear localization signal, which all Mdm proteins contain, is
located in the C-terminal region of the protein. The mRNA is
expressed at a high level in thymus and at lower levels in all
other tissues tested. MDM4 protein produced by in vitro translation
interacts with p53 via a binding domain located in the N-terminal
region of the MDM4 protein. MDM4 shows significant structural
similarity to p53-binding protein MDM2. Two transcript variants,
one protein-coding and the other likely not to be protein-coding,
have been found for this gene.

None

batch dependent

For WB starting dilution is: 1:1000

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.