VASP Antibody

Primary Antibodies

Blue Ice

40 kDa

Vasodilator-stimulated phosphoprotein (VASP) is a member
of the Ena-VASP protein family. Ena-VASP family members contain an
EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E
motifs and targets Ena-VASP proteins to focal adhesions. In the
mid-region of the protein, family members have a proline-rich
domain that binds SH3 and WW domain-containing proteins. Their
C-terminal EVH2 domain mediates tetramerization and binds both G
and F actin. VASP is associated with filamentous actin formation
and likely plays a widespread role in cell adhesion and motility.
VASP may also be involved in the intracellular signaling pathways
that regulate integrin-extracellular matrix interactions. VASP is
regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This VASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the C-terminal region of human VASP.

Vasodilator-stimulated phosphoprotein

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.